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Lion's Mane Capsules 
Lion's Mane CapsulesFrom $20.95From $20.95 -
Turkey Tail Capsules 
Turkey Tail CapsulesFrom $20.95From $20.95 -
Stamets 7® Capsules 
Stamets 7® CapsulesFrom $20.95From $20.95 -
MyCommunity® Capsules 
MyCommunity® CapsulesFrom $20.95From $20.95 -
MycoBotanicals® Brain* Capsules 
MycoBotanicals® Brain* Capsules$31.95$31.95 -
Lion's Mane Powder 
Lion's Mane PowderFrom $31.95From $31.95 -
Reishi Capsules 
Reishi CapsulesFrom $20.95From $20.95 -
Lion's Mane Extract 
Lion's Mane ExtractFrom $20.95From $20.95 -
Stamets 7® Powder 
Stamets 7® PowderFrom $31.95From $31.95 -
Turkey Tail Powder 
Turkey Tail PowderFrom $31.95From $31.95 -
Cordyceps Capsules 
Cordyceps CapsulesFrom $20.95From $20.95 -
Agarikon Capsules 
Agarikon CapsulesFrom $36.95From $36.95 -
Turkey Tail Extract 
Turkey Tail ExtractFrom $20.95From $20.95 -
Breathe* Capsules 
Breathe* CapsulesFrom $20.95From $20.95 -
Reishi Powder 
Reishi Powder$31.95$31.95 -
MycoBotanicals® Microbiome* Powder 
MycoBotanicals® Microbiome* Powder$31.95$31.95 -
MycoBotanicals® Energy* Capsules 
MycoBotanicals® Energy* Capsules$36.95$36.95 -
Reishi Extract 
Reishi ExtractFrom $20.95From $20.95 -
MyCommunity® Powder 
MyCommunity® Powder$31.95$31.95 -
BrainPower Stack® Powder 
BrainPower Stack® Powder$31.95$31.95 -
Turkey Tail & Agarikon Capsule Bundles 
Turkey Tail & Agarikon Capsule BundlesFrom $60.27From $60.27 -
Paul's Favorites Bundle 
Paul's Favorites Bundle$138.28$138.28
Welcome to Host Defense Mushrooms! Founded by Paul Stamets, our mushroom mycelium and fruit bodies grown on our certified organic farm in Washington State are non-GMO, vegan, and gluten-free. We base our formulations on scientifically proven data to ensure quality and safety, which is why we are the best selling mushroom supplement brand in the U.S.ꝉ
A product of Fungi Perfecti, LLC. Building Better Health Since 1980.*
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Immune Support is Just a Spray Away!*
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MycoShield® Winter Mist® Throat Spray 
MycoShield® Winter Mist® Throat SprayFrom $10.95From $10.95 -
MycoShield® Cinnamon Throat Spray 
MycoShield® Cinnamon Throat SprayFrom $10.95From $10.95 -
MycoShield® Peppermint Throat Spray 
MycoShield® Peppermint Throat SprayFrom $10.95From $10.95 -
MycoShield® Licorice Throat Spray 
MycoShield® Licorice Throat SprayFrom $10.95From $10.95 -
MycoShield® Citrus Throat Spray 
MycoShield® Citrus Throat SprayFrom $10.95From $10.95
Why Host Defense?
Founded by Paul Stamets
Pioneered by world-renowned mycologist Paul Stamets to connect people with the power of fungi.
Powered by Mushroom Mycelium
The foundation of every Host Defense supplement and our mission.
Innovative Research & Development
Our in-house R&D team drives groundbreaking research in fungi and wellness.
Climate Positive Commitment
We offset 110 percent of our emissions to create a net positive impact for people and planet.
Exceptional Customer Support
Our friendly, knowledgeable team is here to help at every step.